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As with all medications, there are some side effects of Maxalt to be familiar with. Some of the most common of these includes feeling dizzy, sleepiness, feeling tired or weak, tingling sensations, difficulty concentrating, sweating, shortness of breath, headaches, nausea, dry mouth and diarrhea. More serious common side effects which occur less frequently include blurry vision, neck pain, insomnia, nervousness, increased blood pressure, thirst, indigestion and itching skin. On rare occasions the use of this medication can cause a heart attack or stroke. However, these occurrences typically only happen in people who have risk factors for heart disease.

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Maxalt should not be used by patients taking MAO inhibitors because these types of drugs can prevent the body from properly breaking down Maxalt which increases the risk of side effects developing. People who take St. John's wort regularly are told to stop taking the herb before taking Maxalt as the two used in combination can cause some mild side effects.

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